Short answer: A lock may reduce accidental button presses, but the control sequence and protection vary by device. Check the manual for your exact model before carrying it.

What to check
Look for a physical lock switch or manufacturer-documented button lock. Some draw-activated disposables have no user-operated lock. A common five-click instruction is not universal.
Carry and stop-use guidance
Keep the device separate from keys and other objects. If it activates on its own, becomes hot, or is damaged, stop using and charging it; contact the seller or manufacturer. Never rely on a lock to make a device child-safe.
For battery precautions, see the FDA battery safety guidance. Follow the instructions for your exact device.
FAQ
Do all vapes lock with five clicks?
No. Controls differ by model, and some sealed devices have no such feature.
Can I leave a locked vape where a child can reach it?
No. Store all nicotine products securely out of reach of children and pets.
Nicotine products are for adults of legal age and can be addictive. Keep them away from children and pets.